How to Use Niacinamide in Your Skincare Routine A Brief Guide Can You Use Niacinamide with Retinol Safely? Sachi Skin What to Pair and Avoid with Glutathione Shawill Niacinamide Collagen Glutathione Body Lotion 500ml Combining Glutathione and Niacinamide for skin brightening can be extremely beneficial for your skin. Niacinamide helps reduce pigmentation and dark spots, whereas glutathione helps reduce melanin production, thereby lightening the dark spots Not all skincare ingredients play well together! Mixing the wrong actives can cause irritation, cancel out their benefits, or even damage your skin barrier. Avoid Mixing Vitamin C + Niacinamide