Unveiling the molecular basis of paracetamol induced hepatotoxicity: Interaction of N acetyl p benzoquinone imine with mitochondrial succinate dehydrogenase ScienceDirect Acetaminophen and aspirin toxicity are both high yield, but the injury pattern is very different. Acetaminophen overdose overwhelms glutathione, allowing NAPQI to build up and cause hepatic necrosis. The antidote is N acetylcysteine, which Tox and Hound Fellow Friday What Terror Hath NAPQI Wrought? Measurement of Serum AcetaminophenProtein Adducts in Patients With Acute Liver Failure Gastroenterology Acetaminophen metabolism and NAPQI mediated mitochondrial effects Download Scientific Diagram Paracetamol Toxicity an overview ScienceDirect Topics